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  • What are the Best Fat Burning Compounds?

    There are so many different types of supplements out there that sometimes it can be hard to work out what ones work, and well, what ones are a complete and utter waste of money.

    And fat burners can be some of the worst culprits.

    Fat burning supplements (also known as “thermogenics”) are a branch of supplements that are purported to help you lose weight. As their name suggests, they are ultimately designed to burn more fat, making fat loss easier.

    However, when it comes to this branch of compounds, some are much better than others.

    The problem with some fat burners

    While there are certainly some fat burning supplements that work, there are a large number on the market that promise the world, but actually contain very few (and sometimes, zero) ingredients that have scientific evidence to support their use.

    These supplements rely on good marketing to sell their products, rather than results -- and they are completely useless.

    Which is why we wanted to spend today talking about some of those fat burning compounds that actually work.

    The best fat burning compounds

    When it comes to effective fat burning compounds, they generally act on the body in one of two (or sometimes both) very distinct ways:

    1. They increase your fat metabolism, and;
    2. Enhance your daily energy expenditure

    Taking this into consideration, fat metabolism really just describes the process where your body breaks down fat and uses it for energy.

    Fat burning compounds that do a good job of increasing fat metabolism essentially make your fat more available for energy production. They also speed up the rate at which your body breaks down fat for energy -- both of which cause a large increase in fat metabolism.

    Next up we have energy expenditure.

    Compounds that enhance energy expenditure ultimately increase your metabolic rate (AKA the amount of energy your body burns to survive). By increasing your metabolic rate, these compounds essentially increase the amount of energy you burn every single day -- irrespective of how much you exercise.

    Obviously this increase in daily energy expenditure makes creating a sustained energy deficit easier, increasing fat loss.

    OK, so this is all well and good -- but what are those compounds that actually have these effects on the body?

    Well, here are a few of them…

    Gamma-Butyrobetaine (GBB)

    Gamma-Butyrobetaine (or GBB for short) is a naturally occurring compound that your body uses to synthesise L-Carnitine -- which is a unique amino acid that plays a role helping your body break down and use fats for energy.

    To be more specific, L-carnitine is a primary player in a process known as beta oxidation. This distinct process essentially describes the way your body breaks down fat for energy in the presence of oxygen (think at rest, or during moderate intensity aerobic exercise).

    This means that by supplementing with GBB you can increase fat metabolism, making your body burn more fat for energy. There is also some evidence to suggest that taking it before you start exercise can increase the amount of fat you burn during that bout of exercise [1].

    This makes it a great choice to take before doing some low intensity cardio.


    Rauwolscine is a naturally occurring dirritvie of “yohimbe” -- which is a compound that comes from the yohimbe plant (duh).

    Yohimbe has been used for centuries in traditional eastern cultures to increase energy levels and improve feelings of happiness and emotional wellbeing. Moreover, it has also been shown to help increase weight loss by blocking “alpha-2 adrenergic receptors”.

    This is important, because rauwolscine actually blocks “alpha-2 adrenergic receptors” in a much more effective way than Yohimbe, making it a more potent fat loss supplement [2].

    What does this actually mean?

    Well, alpha-2 receptors are found throughout your brain and your body. When they are activated, they calm the body, lowering heart rate, increasing insulin secretion, and promoting energy storage.

    But by blocking these receptors, rauwolscine reduces fat storage and increases fat metabolism. Moreover, it also increases the release of norepinephrine and epinephrine, which elevates heart rate and energy expenditure.

    This makes it a fat burning option that hits both mechanisms mentioned above.

    Theobromine Extract

    Theobromine is a natural compound found in cacao plants and tea leaves, that has been shown to increase blood flow throughout the body, while also promoting the secretion of key hormones epinephrine and norepinephrine.

    These two hormones are known to increase both heart rate and metabolic rate [3].

    As a result, the supplementation of theobromine can lead to a notable increase in daily energy expenditure, making achieving an energy deficit -- and sustaining long term weight loss -- easier.

    Acetyl L-Carnitine

    I have already outlined above (read GBB) that L-Carnitine is an amino acid that plays a role in the process of beta oxidation -- being the process by which your body breaks down fat for energy.

    This means that supplementing with L-Carnitine can contribute to a larger portion of the energy you burn every single day coming from fat [4].

    I also want to note here that your body has the ability to store up GBB and L-Carnitine -- meaning that supplementing them together increases the amount you have available to facilitate fat metabolism.


    Tyrosine is a unique amino acid found in your body.

    This amino acid is important because it helps your body make dopamine, adrenaline and noradrenaline, and your thyroid hormones -- all of which impact upon your metabolism.

    By increasing dopamine, adrenaline, and norepinephrine secretion, this compound causes a marked increase in energy expenditure.

    But more important is its impact on your thyroid hormones.

    Research has shown that L-Tyrosine can increase “T3” (the most active thyroid hormone) while simultaneously lowering another hormone called “TSH”, which can often be linked to hypothyroidism [4].

    This suggests that L-tyrosine can help regulate your metabolism, which may make it easier to lose fat.

    Synephrine HCL

    Synephrine is a compound found in the peels of citrus plants.

    Synephrine extract appears to impact upon the function of your liver, where it enhances the production and secretion of numerous enzymes that help with energy production.

    Within this, it has also been shown to increase heart rate and energy output.

    Collectively, this has been shown to increase daily energy expenditure while simultaneously boosting your metabolism -- making it one of the most effective fat loss compounds on the planet [5].

    Caffeine Anhydrous

    Lastly we have caffeine -- AKA the big one.

    Caffeine is a naturally occurring stimulant that attaches itself to the “adenosine receptors” within your brain.

    Adenosine is a neurotransmitter that relaxes the brain, making you feel tired. Under normal circumstances, adenosine levels accumulate throughout the day, facilitating your transition into sleep.

    But by blocking these receptors, caffeine increases sensations of alertness, while also boosting the levels of adrenaline, dopamine, and norepinephrine in your brain. This increases your energy output, while also helping mobilise your fat stores for energy.

    Which again speeds up fat loss by making it easier to maintain an energy deficit [6].

    Final Points

    I want to finish this article by outlining that fat burners won't do it all for you. To lose fat you need to exercise hard and eat in an energy deficit over a prolonged period of time -- however, fat loss supplements can make getting into a daily energy deficit easier.

    In this manner, they are a great option to speed up the fat loss process.

    Before supplementing with a fat loss supplement you should always seek advice from a medical professional before commencing supplementation (you know, just to be safe), as many exhibit stimulant-like effects on the body.



    1. Prasertsri, Piyapong, et al. "Cashew apple juice supplementation enhanced fat utilization during high-intensity exercise in trained and untrained men." Journal of the International Society of Sports Nutrition 10.1 (2013): 1-6.
    2. Perry, Bruce D., and David C. U'Prichard. "[3H] Rauwolscine (?-yohimbine): a specific antagonist radioligand for brain ?2-adrenergic receptors." European journal of pharmacology 76.4 (1981): 461-464.
    3. Baggott, Matthew J., et al. "Psychopharmacology of theobromine in healthy volunteers." Psychopharmacology 228.1 (2013): 109-118.
    4. Huang, Amy, and Kevin Owen. "Role of supplementary L-carnitine in exercise and exercise recovery." Acute Topics in Sport Nutrition. Vol. 59. Karger Publishers, 2012. 135-142.
    5. Haaz, S., et al. "Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update." Obesity reviews 7.1 (2006): 79-88.
    6. Ferreira, G. A., et al. "Does caffeine ingestion before a short-term sprint interval training promote body fat loss?." Brazilian Journal of Medical and Biological Research 52.12 (2019).
  • Top 3 Ingredients You Must Use for Fat Burning

    Next to building muscle mass, the quest to lose weight and burn fat is the most popular fitness goal. Shedding excess weight and extra adipose tissue doesn't just help you look good, it's also been shown to be great for your health. Excess adipose tissue has been associated with higher levels of cardiovascular disease and high blood pressure.


    If weight loss is at the top of your fitness goals, supplementation, as a part of a healthy diet and exercise program, may be able to promote a higher level of fat burning. Let's take a look at the top 3 supplement ingredients that you need to use to burn more fat and achieve your weight loss goals.


    1. L-Carnitine

    Hands down, one of the most popular fat burning ingredients, L-Carnitine has been proven time and time again to be effective at supporting weight loss.


    L-Carnitine encourages the use of fat as energy by helping it into the mitochondria of a cell. Once inside, the mitochondria will burn the fat as a fuel source.


    L-Carnitine has also been suggested to be an effective anti-inflammatory. Not only can it promote fat burning but it may also alleviate inflammation in joints, especially if you often feel stiff or sore post-workout. (1-3)


    • Suggested dosage: 4 grams per day


    1. CLA

    Is your goal to burn extra calories?
    Want to also build muscle?

    Need to protect your current level of muscle while losing weight?

    CLA may be the perfect supplement for you.


    Conjugated Linoleic Acid, more commonly known as CLA, has been shown in a number of studies to support fat loss AND muscle building.


    CLA is suggested to support fat burning and long-term weight loss. While it is promoting weight loss, it can also be a powerful ally to muscle tissue. It does so by helping with protein synthesis in the body. This, in turn, will help prevent protein catabolism, or the breakdown of muscle tissue. Protein synthesis can also be helpful when trying to increase muscular size. (4-6)


    • Suggested dosage: 5 grams per day


    1. Guarana

    Last but certainly not least, we have guarana. This is a potent herbal remedy that has been used in the Amazonian jungles for hundreds of years as a communal drink that promotes overall health. Science has finally shed light on the benefits of guarana with the most popular being energy boosting and weight loss support.


    Guarana has been shown in several studies to be as effective as caffeine when it comes to energy levels. For those who are caffeine sensitive, guarana may be the next best thing as it doesn't include the characteristic anxiety that comes with caffeine use.


    On top of more energy, guarana has been suggested to improve cognitive ability by boosting focus and alertness.


    Finally, guarana may be able to promote an elevated metabolic response that support overall weight loss. (7-8)


    • Suggested dosage: 700 milligrams per day



    Taken as a part of a healthy diet and exercise program, L-Carnitine, CLA, and Guarana may be the powerful trio you need to see better weight loss results. Want to save money and find all three of these ingredients in one place? Make your own supplement!


    With the Amino Z Supplement Builder, you can create your own supplement with the ideal dosages suggested above. Check out the Amino Z Supplement Builder now to get started on your perfect fat burning supplement.



    1. Brandsch C, Eder K. Effect of L-carnitine on weight loss and body composition of rats fed a hypocaloric diet. Ann Nutr Metab. 2002;46(5):205-10.
    1. Malek Mahdavi A, Mahdavi R, Kolahi S. Effects of l-Carnitine Supplementation on Serum Inflammatory Factors and Matrix Metalloproteinase Enzymes in Females with Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. J Am Coll Nutr. 2016 Sep-Oct;35(7):597-603. Epub 2016 Mar 2.
    1. Smeland OB, Meisingset TW, Borges K, Sonnewald U. Chronic acetyl-L-carnitine alters brain energy metabolism and increases noradrenaline and serotonin content in healthy mice. Neurochem Int. 2012 Jul;61(1):100-7. doi: 10.1016/j.neuint.2012.04.008. Epub 2012.
    1. Whigham LD, Watras AC, Schoeller DA. Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans. Am J Clin Nutr. 2007 May;85(5):1203-11.
    1. Vaughan RA, Garcia-Smith R, Bisoffi M, Conn CA, Trujillo KA. Conjugated linoleic acid or omega 3 fatty acids increase mitochondrial biosynthesis and metabolism in skeletal muscle cells. Lipids Health Dis. 2012;11:142.
    1. DeLany, James P., et al. (1999). Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology276, 4, R1172-R1179.
    1. Kennedy DO, Haskell CF, Wesnes KA, Scholey AB. Improved cognitive performance in human volunteers following administration of guarana (Paullinia cupana) extract: comparison and interaction with Panax ginseng. Pharmacol Biochem Behav. 2004 Nov;79(3):401-11.
    1. Moustakas D, Mezzio M, Rodriguez BR, Constable MA, Mulligan ME, Voura EB. Guarana Provides Additional Stimulation over Caffeine Alone in the Planarian Model. Holscher C, ed. PLoS ONE. 2015;10(4):e0123310. doi:10.1371/journal.pone.0123310.
  • EHP Labs OxyShred vs. Victory Labs Xenevar

    Extreme energy levels and fat burning go hand in hand when it comes to thermogenic supplements. The best brands will allow you to trigger a higher level metabolic response while enjoying the benefits of focus, alertness, and energy. Today, we are looking at two of the heavy hitters in the thermogenic world: EHP Labs OxyShred and Victory Labs Xenevar. Let's review their respective formulas to see which one is worth using in your daily supplement program.


    EHP Labs OxyShred

    Where can I buy it?

    • Here's where you can buy EHP Labs OxyShred.


    Pros of EHP Labs OxyShred

    EHP Labs OxyShred is a thermogenic that has been uniquely designed for fat burning with extreme energy as a positive side effect. The EHP Labs OxyShred formula may even be considered too much for those who are inexperienced with thermogenic compounds. You can take that as a positive or a negative depending on your sensitivity to the ingredients.


    There's no doubt that the team over at EHP Labs did their homework with the formula. It features many scientifically backed ingredients including Conjugated Linoleic Acid, African Wild Mango, and 1, 3, 7 Trimethylxanthine that have been shown to boost fat burning and energy levels. (1-3)


    Cons of EHP Labs OxyShred

    The only issue that we have with EHP Labs Oxyshred is that it has a proprietary blend for its fat burning and energy boosting compounds. This means that you don't know exactly how much of each ingredient you're getting. Still, with that said, you can assume that each ingredient may be properly (if not almost properly) dosed at the ideal levels due to the size of the blend. For example, the thermogenic blend is almost 7 grams. That leaves a lot of elbow room for the dosing of these ingredients.



    Victory Labs Xenevar

    Where can I buy it?

    • Here's where you can buy Victory Labs Xenevar.


    Pros of Victory Labs Xenevar

    The user reviews on Xenevar have helped to draw plenty of positive attention its way. This product is all about fat burning, featuring tried and true compounds like L-Carnitine Tartrate, Guarana, and Raspberry Ketones. (4-6) It also contains a trademarked version of Fulvic Acid known as OxyGold. Victory Labs claims that Fulvic Acid can improve the uptake and assimilation of all the other compounds buts studies are inconclusive. Still, if it does play a role in nutrient assimilation, that's excellent news for you.


    Cons of Victory Labs Xenevar

    Just like with EHP Labs OxyShred, we were disappointed to see that Victory Labs Xenevar had a proprietary blend for a formula. What you do know is that you're getting almost 5 grams of a great stack of thermogenics and energy boosters. 5 grams is a decent amount and with L-Carnitine as the first ingredient on the list, there's a good chance you are getting the right dosing, if not close to it.


    Which One Should You Choose?

    These two thermogenic products are tough to choose between. They both have their strengths yet share the same weakness. EHP Labs has the bigger following as evidenced by the amount of user reviews and positive feedback reports online. You're also getting more out of the formula itself. With that said, Victory Labs Xenevar is holding its own amidst a crowded market. We would recommend trying both and seeing which one your body agrees with more. Either way, you're sure to experience high energy and incredible fat burning.



    1. Leah D Whigham, Abigail C Watras, and Dale A Schoeller. Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans. Am J Clin Nutr May 2007. Vol. 85 no. 5 1203-1211.
    1. Judith L Ngondi, Julius E Oben, and Samuel R Minka. The effect of Irvingia gabonensis seeds on body weight and blood lipids of obese subjects in Cameroon. Lipids Health Dis. 2005; 4: 12. Published online 2005 May 25.
    1. Costill DL, Dalsky GP, Fink WJ. Effects of caffeine ingestion on metabolism and exercise performance. Medicine and Science in Sports [1978, 10(3):155-158]
    1. Brandsch C, Eder K. Effect of L-carnitine on weight loss and body composition of rats fed a hypocaloric diet. Ann Nutr Metab. 2002;46(5):205-10.
    1. Kennedy DO, Haskell CF, Wesnes KA, Scholey AB. Improved cognitive performance in human volunteers following administration of guarana (Paullinia cupana) extract: comparison and interaction with Panax ginseng. Pharmacol Biochem Behav. 2004 Nov;79(3):401-11.
    1. Morimoto C, Satoh Y, Hara M, Inoue S, Tsujita T, Okuda H. Anti-obese action of raspberry ketone. Life Sci. 2005 May 27;77(2):194-204. Epub 2005 Feb 25.
  • MuscleTech Performance Series Nitro Tech Ripped vs. BSN Isoburn

    One of the newest crazes to hit the supplement market is thermogenic protein. Just like the name implies, thermogenic protein has a foundation of muscle building protein, which is supported by fat burning ingredients such as L-Carnitine and Yohimbe. Two of the biggest giants in the industry have grabbed on to the new protein craze: MuscleTech Performance series Nitro Tech Ripped vs. BSN Isoburn. Let's review the pros and cons of both of these brands to see which one has a better thermogenic protein product.


    MuscleTech Performance Series Nitro Tech Ripped

    Where can I buy it?

    • Here's where you can buy MuscleTech Performance Series Nitro Tech Ripped.


    Pros of MuscleTech Performance Series Nitro Tech Ripped

    MuscleTech isn't messing around when it comes to this thermogenic protein. Right out of the gate, you're getting 30 grams of protein from a unique blend of Whey Peptides, Whey Protein Isolate, and Whey Protein Isolate. This means that MuscleTech is going to be ideal for a post-workout treat. The fast-acting amino acids may help to support recovery, trigger protein synthesis, and promote lean muscle tissue growth. (1-7)


    MuscleTech also features a great line-up of some proven fat burning thermogenics. Some of these ingredients have been shown to promote fat loss while boosting your metabolic rate. (8-10) Here's the full list:


    • L-Carnitine L-Tartrate
    • CLA (Conjugated Linoleic Acid)
    • canephora robusta extract (bean) (Robusta Coffee)
    • Green Tea Extract (as Camellia sinensis) (leaf)
    • Rose Hip Extract (as Rosa canina) (fruit)
    • Kelp


    Cons of MuscleTech Performance Series Nitro Tech Ripped

    The only issue we have with MuscleTech Performance Series Nitro Tech Ripped is the dosage of some of the thermogenic ingredients is under-dosed. If you look at the study samples and how big of a dose they used to get those results, MuscleTech cuts it a bit short. With that said, this is a protein supplement first and foremost and a weight loss support second. It's like a protein shake with a little boost of fat burning but it's still a protein shake.


    BSN Isoburn

    Where can I buy it?

    • Here's where you can buy BSN Isoburn.


    Pros of BSN Isoburn

    Just like MuscleTech, Isoburn from BSN focuses on fast digesting proteins. That means it's going to be ideal after your workout or first thing upon waking. Remember, as we mentioned above, those amino acids from the isolate may help to boost muscle building and recovery.


    As to its thermogenic formula, it features a decent line-up of thermogenic compounds:


    • Green Coffee Extract
    • Blue-Green Algae Extract
    • Beta-Carotene
    • Pomegranate Extract
    • L-Carnitine Tartrate
    • Choline Bitartrate
    • Banaba Extract


    Just like MuscleTech, it's offering plenty of protein for muscle building goals and a select line of thermogenic compounds that may support weight loss.


    Cons of BSN Isoburn

    First, BSN doesn't compare with MuscleTech in the gram for gram category. MuscleTech provides 30 grams of protein while BSN is only giving 20 grams.


    The bigger problem is the thermogenic formula. Since BSN uses proprietary blends, you have no idea how much of each ingredient you're getting. Considering the blend is only 1 gram, you can rest assured that it won't be much. One way to remedy this would be to double the dose. That would effectively give you twice the protein and fat burning agents but it would also burn through your wallet twice as fast.



    Both brands are great examples of a real thermogenic protein but it's easy to see why we would go with MuscleTech Performance Series Nitro Tech Ripped. It has more protein and more fat burning ingredients than BSN. With that said, BSN Isoburn is still a decent protein that would be a good choice, especially if it was on sale. For a post-workout protein that supports fat burning, try one of these great thermogenic proteins.



    1. Phillips SM1, Van Loon LJ. Dietary protein for athletes: from requirements to optimum adaptation. J Sports Sci. 2011;29 Suppl 1:S29-38. doi: 10.1080/02640414.2011.619204.
    1. Tsutsumi R, Tsutsumi YM. Peptides and proteins in whey and their benefits for human health. Austin J Nutri Food Sci 2014;1(1): 1002
    1. Blomstrand E, Eliasson J, Karlsson HK, Köhnke R. Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise. J Nutr. 2006 Jan;136(1 Suppl):269S-73S.
    1. Norton, Layne, Layman, Donald. Leucine Regulates Translation Initiation of Protein Synthesis in Skeletal Muscle after Exercise. J. Nutr. February 2006 vol. 136 no. 2 533S-537S.
    1. Negro M, Giardina S, Marzani B, Marzatico F. Branched-chain amino acid supplementation does not enhance athletic performance but affects muscle recovery and the immune system. J Sports Med Phys Fitness. 2008 Sep;48(3):347-51.
    1. Mourier A, Bigard AX, de Kerviler E, Roger B, Legrand H, Guezennec CY. Combined effects of caloric restriction and branched-chain amino acid supplementation on body composition and exercise performance in elite wrestlers. Int J Sports Med. 1997 Jan;18(1):47-55.
    1. De Lorenzo A, Petroni ML, Masala S, Melchiorri G, Pietrantuono M, Perriello G, Andreoli A. Effect of acute and chronic branched-chain amino acids on energy metabolism and muscle performance. Diabetes Nutr Metab. 2003 Oct-Dec;16(5-6):291-7.
    1. Venables MC, Hulston CJ, Cox HR, Jeukendrup AE. Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans. Am J Clin Nutr. 2008 Mar;87(3):778-84.
    1. Brandsch C, Eder K. Effect of L-carnitine on weight loss and body composition of rats fed a hypocaloric diet. Ann Nutr Metab. 2002;46(5):205-10.
    1. Igho Onakpoya, Rohini Terry, and Edzard Ernst. The Use of Green Coffee Extract as a Weight Loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. Gastroenterol Res Pract. 2011; 2011: 382852.
  • Technology Wins Over Obesity

    Experts have developed a tiny pocket sized piece of technology which notifies users of if and when their body is burning fat for energy.
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