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  • Supplements Used in Traditional Chinese Medicine for Millennia may Help Improve Running Times and Performance, According to Results of a Human Study

    Traditional Chinese medicine (TCM) has brought some effective remedies to the West over the past century, allowing millions to benefit from them.

    The results of a new study indicate that a combination of two herbs used in TCM can help significantly improve running times, and promote subsequent recovery.

    The Supplements In Question

    The study, undertaken by researchers from Kaohsiung Medical University in Thailand, used a combination of Astragalus membranaceus and Angelica sinesis in a 5 to 1 ratio and marketed as a product known as Danggua Buxue Tang (DBT).

    The Study

    The study analyzed the data obtained from 36 men that identified as recreationally active runners, who consumed the combination DBT supplement before beginning a 13 km run, or a placebo over the course of 11 days.

    The Results

    The men that consumed DBT displayed on average, 12 minutes earlier completion of the run, equating to approximately 14% faster time when compared to the men that were given placebo. By the time the study was in its eighth day, men assigned DBT were able to run the 13 km distance at maximum intensity, whereas at the inception of the trial, this was not possible.

    The Role of DBT in the Trial

    DBT has been used in traditional Chinese medicine for well over three millennia, where it was reported to improve physical activity significantly. However, this was all anecdotal evidence until this study was undertaken.

    In particular, DBT appears to play an important role in the regulation of serum iron levels. Many athletes fall victim to the development of iron deficiency anemia as a result of rigorous training [1], even though iron's its role in physical performance is typically underestimated.

    However, ensuring post exercise serum iron levels are maintained is critical to your overall recovery. In athletes, iron levels may be compromised as a result of:

    • Hemolysis as a results of exercise, owing to oxidative stress and mechanical force placed on muscles and joints.
    • Gastrointestinal and urinary tract blood loss as a result of compromised visceral blood circulation during exercise (causing microscopic tears).
    • Reduced iron absorption due to increased levels of hepcidin post-workout (brought on by acute inflammation), and also iron sequestration in macrophage cells.

    Following a workout, hepcidin levels are elevated [2], leading to decreased iron transport and a reduction in serum levels.

    Supplementation with DBT reduces the impact of hepcidin post workout [3], allowing for increased serum iron levels and accelerated recovery.

    Other Findings

    Subjects that supplemented with DBT during the trial also displayed lower levels of the oxidative marker malondialdehyde in blood 72 hours following exercise, along with an immediate 63% increase in serum iron levels post exercise, and an average 31% elevation after three days of rest.

    Conclusion

    Even though anecdotal evidence has been pointing to improved physical performance attributed to DBT supplements for millennia, this is the first study that confirmed these findings. What this indicates is that these supplements used in TCM may find a role as an ergogenic aid in your training program.

    References

    1. Chih-Wei Chang, Chao-Yen Chen et al. (2018) Repressed Exercise-Induced Hepcidin Levels after Danggui Buxue Tang Supplementation in Male Recreational Runners. Nutrients, 10(9), 1318
    2. Marjan Wouthuyzen-Bakker, Sander van Assen (2015) Exercise-induced anemia: a forgotten cause of iron deficiency anemia in young adults. British Journal of General Practice 65(634):268–269 doi: [10.3399/bjgp15X685069]

    3.Raúl Domínguez,  Antonio Jesús Sánchez-Oliver et al. (2018) Effects of an Acute Exercise Bout on Serum Hepcidin Levels. Nutrients. 2018 Feb; 10(2): 209 doi:  [10.3390/nu10020209]

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